Patents

  1. Hanes J, Fiegel J, and Fu J, Biodegradable polymer compositions: Compositions and uses related thereto, U.S. Patent No. 7,163,697 B2.  Granted January 16, 2007.
  2. Edwards, D.A., Caponetti, G., Hrkach, J.S., Lotan, N., Hanes, J., Langer, R and  Ben-Jebria, A.A, Porous Particles comprising excipients for deep lung delivery, U.S. Patent No. 6,740,310.  Granted May 25, 2004.
  3. Edwards, D.A., Caponetti, G., Hrkach, J.S., Lotan, N., Hanes, J., Ben-Jebria, A.A., and Langer, R., Aerodynamically light particles for pulmonary drug delivery, U.S. Patent No. 6,635,283.  Granted October 21, 2003.
  4. Edwards, D.A., Caponetti, G., Hrkach, J.S., Lotan, N., Hanes, J., Ben-Jebria, A.A., and Langer, R., Aerodynamically light particles for pulmonary drug delivery, U.S. Patent No. 6,503,480.  January 7, 2003. (Continuation of U.S. Patent Application 09/562,988, filed May 1, 2000, which is a continuation of U.S. Patent No. 6,136,295).
  5. Edwards, D.A., Caponetti, G., Hrkach, J.S., Lotan, N., Hanes, J., Langer, R., Ben-Jebria, A. Amorphous porous particles for deep lung delivery, U.S. Patent No. 6,447,752.  September 10, 2002. (Continuation of U.S. Patent No. 6,254,854)
  6. Edwards, D.A., Caponetti, G., Hrkach, J.S., Lotan, N., Hanes, J., Langer, R., Ben-Jebria, A. Porous particles for deep lung delivery, U.S. Patent No. 6,447,753. September 10, 2002. (Continuation of U.S. Patent No. 6,254,854)
  7. Edwards, D.A., Caponetti, G., Hrkach, J.S., Lotan, N., Hanes, J., Langer, R., Ben-Jebria, A. Porous particles for deep lung delivery, U.S. Patent No. 6,254,854.  July 3, 2001.
  8. Hanes, J., Edwards, D.A., Evora, C., and Langer, R., Particles incorporating surfactants for pulmonary drug delivery, U.S. Patent RE37,053.  Granted February 13, 2001.  Continuation of U.S. Patent No. 5,855,913.
  9. Edwards, D.A., Caponetti, G., Hrkach, J.S., Lotan, N., Hanes, J., Ben-Jebria, A.A., and Langer, R., Aerodynamically light particles for pulmonary drug delivery, U.S. Patent No. 6,136,295.  Granted October 24, 2000. (Divisional of U.S. Patent No. 5,874,064)
  10. Edwards, D.A., Caponetti, G., Hrkach, J.S., Lotan, N., Hanes, J., Ben-Jebria, A.A., and Langer, R., Aerodynamically light particles for pulmonary drug delivery, U.S. Patent No. 5,874,064.  Granted February 23, 1999.
  11. Hanes, J., Edwards, D.A., Evora, C., and Langer, R., Particles incorporating surfactants for pulmonary drug delivery, U.S. Patent No. 5,855,913.  Granted January 5, 1999.
  12. Drug insolubilization for sustained pulmonary drug delivery, 1998.
  13. Hanes J, Fu J (2006) Functionalized Poly(ether-anhydride) Block Copolymers (PCT Publication Number: WO/2006/063249 A2).
  14. Hanes J, Dawson M, Wirtz D, Fu J, Krauland E (2005) Drug and gene carrier particles that rapidly move through mucus barriers (PCT Publication Number: WO/2005/072710)
  15. Edwards, D.A., Hanes, J., Evora, C., Langer, R., Vanbever, R., Mintzes, J., Wang, J., Chen, D., Preparation of Particles for Inhalation. (PCT Pending)
  16. Lai SK, Hanes J, Large nanoparticles that cross mucosal barriers (PCT Pending).
  17. Lai SK, Yang M, Wang Y.,  Mert O, Ensign L, Hanes J, Compositions and Methods Relating to Reduced Mucoadhesion (PCT Publication Number: WO 2012061703 A1 20120510.
  18. Lai SK, Hanes J, Compositions and Methods for Enhancing Transport Through Mucus (PCT Publication Number: WO 2008/030557 A3)
  19. Hanes J, Nance E, Woodworth G, Large Nanoparticles that Penetrate Tissue (PCT Publication Number: WO 2012039979 A2 20120329)
  20. Lai S, Wang Y Y, ­­­­­Cone R, Hanes J, Compositions and Methods for Reducing Particle Penetration Through Mucus Barrier (PCT Publication Number: WO 2009089070 A2 20090716)
  21. Lutty G, Hanes J, Stark W, Yoshida J, Boylan N, Xu, Q, Method of Gene or Drug to Transplanted Cornea (Patent Pending: P11437-01)
  22. Hanes J, Khan Y, Lai SK, Kashiwabuchi R, Behrens A, McDonnell P, Mucus-penetrating and ligand-binding nanoparticles for the sustained delivery of medications to the eye following topical application (Patent Pending: P11200-01)
  23. McDonnell PJ, Behrens A, Hanes J, Kashiwabuchi R, Khan Y, Lai SK, Intrastromally Injected Nanoparticles for Sustained Delivery of Medications to the Cornea (Patent Pending; 61/308,035)
  24. McDonnell PJ, Behrens A, Hanes J, Kashiwabuchi R, Khan Y, Lai SK, Intracameral Injection of Nanoparticles for Sustained Delivery of Medications to the Anterior Chamber (Patent Pending; 61/307,042)
  25. McDonnell PJ, Behrens A, Hanes J, Kashiwabuchi R, Khan Y, Lai SK, Sustained Medication Delivery to the Vitreous Chamber and Retina by Intravitreal Injection Nanoparticles (Patent Pending; 61/308,053)
  26. Sustained Delivery of Therapeutic Agents to an Eye Compartment”, International Application No. PCT/US2011/026321, (International Filing Date: February 25, 2011)
  27. Fu J, Hanes J, Yang M, Polymer-based compositions and methods for treatment of peritoneal disorders, (PCT Publication Number: WO 2011084458 A2 20110714)
  28. Suk J, Hanes J, Mucus Penetrating Gene Carriers, PCT/US2012/024344,( International Filing Date: February 8, 2012)
  29. Ensign L, Cone, R, Hanes J, Method to Achieve Rapid and Uniform Drug Distribution at a Mucosal Surface (Patent Pending: P11383-01)
  30. Boylan N, Hanes J, Kim A, Suk J, Method(s) of Enhancing Gene Carrier Transport in Human Mucus Secretions (Patent Pending; C11808, ROI Filling Date:12/09/2011)
  31. Boylan N, Hanes J, Schneider C, Xu Q, Methods to prepare polymer nanoparticles with both high drug loading and high density PEG coatings (Patent Pending; C11815, ROI Filling Date:12/13/2011)
  32. Boylan N, Hanes J, Xu Q, Biodegradable stealth nanoparticles prepared by a novel self-assembly emulsification method (Patent Pending; C11814, ROI Filling Date:12/13/2011)
  33. Nanocrystals, compositions, and methods that aid particle transport in mucus, (US. Provisional Application No. 61/642,227, Filing Date: 5/03/2012)
  34. Chan K, Yu T, Yang M, McMahon M, Hanes J, Lipid-based drug carriers for rapid penetration through mucus linings
  35. Development of drug loaded microfiber sutures for ophthalmic application
  36. Method(s) of enhancing DNA nanoparticles mediated gene transfer