Facilities
The Johns Hopkins research community is extremely diverse and rich. More than 50 State-of-the-Art Core Facilities are within walking distance on the JHU School of Medicine Campus, including 1H NMR and 13C NMR, drug synthesis, pharmacokinetic/pharmacodynamic evaluation, pathology, biostatistics, imaging, microscopy, sequencing, and a microinjection facility for generation of transgenic mice. Core facilities within the Wilmer Eye Institute include electron microscopy, confocal microscopy, biostatistics, and bioinformatics. There are investigators with expertise in essentially all areas that are available for consultation. The PI’s collaborate with many outstanding investigators, both inside and outside the eye community. There is a strong eye research community that has several seminar series and great opportunities for collaboration and consultation.
In addition to the Center for Nanomedicine, another 27,000 sq ft of the Robert H. and Clarice Smith Building (5th floor—adjacent to the CNM) is dedicated to Biomedical Engineers, many of whom work on biomaterials and drug delivery. Dr. Hanes is also Director of Therapeutics for the Institute for NanoBioTechnology at Johns Hopkins, which includes more than 200 faculty involved research at the intersection of nanotechnology and medicine. The Center for Nanomedicine has an Animal Surgery and Housing Suite on site with long-term animal housing capability and the ability to perform studies with level 2 pathogens. The Center also regularly uses three other full-service animal facilities on campus within 5 min walk, where animals are also housed in controlled climate environments and cared for by in-house animal staff.
The Microscopy and Imaging Core Facility (MICF) of the Wilmer Eye Institute is located on the mezzanine level of the Robert H. and Clarice Smith Building in 1,100 square feet of dedicated laboratory space. The facility provides state of the art light and electron microscopic instruments and consultation to researchers at the Wilmer Eye Institute. Equipment at MICF include Zeiss LSM 510 Meta Confocal and Zeiss LSM 510 Meta Offline Workstation, Hitachi H7600 TEM with Digital and Film Cameras, Leica Ultracut UCT Ultramicrotome and Knifemaker, Nikon TU2000 Inverted Microscope with Spot RT Digital Camera, and Microm HM 500 M Cryostat. Unrestricted access to a Synergy 2 Multi-Mode microplate reader located in the Smith Bldg.
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