Technologies

Nanomedicine for Eye Injections

Filed in Technologies by on October 17, 2013 0 Comments
Nanomedicine for Eye Injections

iris100x100Topical application of eye drops is the most common way to deliver drugs to the eye to treat eye diseases. However, turnover of the tear …

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Brain-penetrating Particles

Filed in Technologies by on October 17, 2013 0 Comments
Brain-penetrating Particles

BRAIN-PENETRATING PARTICLESIn all tissues, including the brain, there is a dense matrix of structural proteins referred to as the extracellular space (ECS). In order to spread …

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Mucus-penetrating Particles

Filed in Technologies by on October 17, 2013 0 Comments
Mucus-penetrating Particles

nanoparticlesAll exposed entry points to the body (e.g. the airways, gastrointestinal tract, female reproductive tract, eyes) are coated with mucus. Mucus protects our epithelial surfaces …

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Non-Viral Gene Vectors

Filed in Technologies by on August 9, 2013
Non-Viral Gene Vectors

capsul-100x100Localized gene therapy is an attractive strategy to treat a variety of life-threatening diseases, spanning genetic disorders, infectious diseases and cancers. However, this approach has …

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Commercialization

Filed in Technologies by on August 9, 2013

The mucus-penetrating particle technology has been commercialized by two companies, Kala Pharmaceuticals and Graybug, both founded by Dr. Justin Hanes, Director of the Center for …

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Technologies

Filed in Technologies by on April 23, 2013
Technologies

Nanotechnology is a powerful tool used for therapeutics and diagnostics to better understand, prevent, treat, and cure many diseases afflicting people today. We have developed …

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Disease Targeting

Filed in Technologies by on April 20, 2013
Disease Targeting

Selected Publications

  • Chan KW, Liu G, Song X, Kim H, Yu T, Arifin DR, Gilad AA,¬†Hanes J, Walczak P, van Zijl PC, Bulte JW,

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Gene Vectors

Filed in Technologies by on April 20, 2013
Gene Vectors

gene-vecLocalized gene therapy is an attractive strategy to treat a variety of life-threatening diseases, spanning genetic disorders, infectious diseases and cancers. However, this approach has …

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Dendrimers

Filed in Technologies by on April 20, 2013
Dendrimers

dendrimerDendrimers are tree-like nanostructured polymers, synthesized with a well-defined size. Even though there are a wide range of dendrimers with differing building blocks, ¬†PAMAM dendrimers …

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Nanoparticles

Filed in Technologies by on April 20, 2013
Nanoparticles

nanoNanoparticles are spherical structures that can be made with numerous fabrication techniques. Nanoparticles can be made spanning a wide range of diameters, typically ranging from …

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