Publications 2014

  1. Yang M, Wang Y-Y, Lai SK, Yu T, Zeng Q, Miao B, Ensign L, Chih-Yin J, Wu T-C, Hung C-F, Hanes J. (2014) Vaginal delivery of paclitaxel via nanoparticles with non-mucoadhesive surfaces suppresses cervical tumor growth, Adv Healthc Mater, 3(7):1044-52.
  2. Yang M, Lai SK, Yu T, Wang Y-Y, Happe C, Zhong W, Zhang M, Anonuevo A, Fridley C, Hung A, Fu J, Hanes J.  (2014) Nanoparticle penetration of human cervicovaginal mucus: The effect of polyvinyl alcohol, J Control Release, 192:202-8.
  3. Kannan RM, Nance E, Kannan S, Tomalia DA. (2014) Emerging concepts in dendrimer-based nanomedicine: from design principles to clinical applications, J. Intern Med, 276(6):579-617.
  4. Mishra MK, Beaty CA, Lesniak WG, Kambhampati SP, Zhang F, Wilson MA, Blue ME, Troncoso JC, Kannan S,  Johnston MV, Baumgartner WA, Kannan RM. (2014) Dendrimer brain uptake and targeted therapy for brain injury in a large animal model of hypothermic circulatory arrest, ACS Nano, 8(3):2134-2147.
  5. Benchaala I, Mishra MK, Wykes SM, Hali M, Kannan RM, Whittum-Hudson JA. (2014) Folate-functionalized dendrimers for targeting to Chlamydia-infected tissues in a mouse model of reactive arthritis, Int J Pharm, 466(1-2):258-65.
  6. Burd I, Zhang F, Dada T, Mishra MK, Borbiev T, Lesniak WG, Baghlaf H, Kannan S, Kannan RM. (2014) Fetal uptake of intra-amniotically delivered dendrimers in a mouse model of intrauterine inflammation and preterm birth, Nanomedicine, 10(6):1343-51.
  7. Yang F, Manitiu M, Kriegel R, Kannan RM. (2014) Structure, Permeability, and Rheology of Supercritical CO2 Dispersed Polystyrene-Clay Nanocomposites, Polymer, 55(16):3915-24.
  8. Suk JS, Kim AJ, Trehan K, Schneider CS, Cebotaru L, Woodward OM, Boylan NJ, Boyle MP, Lai SK, Guggino WB, Hanes J. (2014) Lung Gene Therapy with Highly Compacted DNA Nanoparticles that Overcome the Mucus Barrier, J Control Release, 178:8-17.
  9. Yang M, Yu T, Wood J, Tang BC, Wang YY, Zeng Q, Fu J, Chuang CM, Lai SK, Wu TC, Hung CF, Hanes J. (2014) Intraperitoneal delivery of paclitaxel by poly(ether-anhydride) microspheres effectively suppresses tumor growth in a murine metastatic ovarian cancer model, Drug Del Transl Res, 4:203-209.
  10. Chan KWY, Yu T, Yuan Q, Liu Q, Yang M, Patel H, Liu G, Kinzler K, Vogelstein B, Bulte JWM, van Zijl PCM, Hanes J, Zhou S, McMahon MT. (2014) A diaCEST MRI approach for monitoring liposomal accumulation in tumors, J Control Release, 180:51-9.
  11. da Silva AL, Martini S, Abreu SC, Samary CdS, Diaz BL, Fernezlian S, Sá VK, Capelozzi VL, Boylan N, Goya R, Suk JS, Hanes J, Rocco PRM, Morales MM. (2014) DNA nanoparticle-mediated thymulin gene therapy prevents airway remodeling in experimental allergic asthma, J Control Release, 180:125-33.
  12. Ensign LM, Cone R, Hanes J. (2014) Nanoparticle-based drug delivery to the vagina: A review, J Control Release, 190:500-514.
  13. Schuster BS, Kim AJ, Kays JC, Kanzawa MM, Guggino WB, Boyle MP, Rowe SM, Muzyczka N, Suk JS, Hanes J. (2014) Overcoming the cystic fibrosis airway mucus barrier to leading adeno-associated virus gene therapy vectors, Molec Ther, 22(8):1484-1493.
  14. Pan-in P, Wanichwecharungruang S, Hanes J, Kim AJ. (2014) Cellular trafficking and anticancer activity of Garcinia mangostana extract-encapsulated polymeric nanoparticles, Int J Nanomed, 9(1):3677-3686.
  15. Nance E, Timbie K, Miller GW, Song J, Louttit C, Burke C, Klibanov AL, Shih T-Y, Swaminathan G, Tamargo RJ, Woodworth GF, Hanes J, Price R. (2014)Non-invasive delivery of stealth, brain-penetrating nanoparticles across the blood-brain barrier using MRI-guided focused ultrasound, J Control Release, 189:123-32.
  16. Woodworth GF, Dunn GP, Nance EA, Hanes J, Brem H (2014) Emerging insights into barriers to effective brain tumor therapeutics, Front Oncol, 4:126. doi: 10.3389/fonc.2014.00126.
  17. Kim AJ, Woodworth GF, Boylan NJ, Suk JS, Hanes J. (2014) Highly compacted pH-responsive DNA nanoparticles mediate transgene silencing in experimental glioma, J Mater Chem B Mater Biol Med. 2(46):8165-8173.
  18. Birjiniuk A, Billings N, Nance E, Hanes J, Ribbeck K, Doyle P. (2014) Single particle tracking reveals spatial and dynamic organization of the “E. coli biofilm matrix”, New J Phys, 116(8):085014.
  19. Liu L, Houser GH, Birket SE, Chu KK, Diephuis BJ, Wilsterman EJ, Dierksen G, Mazur M, Shastry S, Li Y, Smith AT, Schuster BS, Hanes J, Grizzle WE, Sorscher EJ, Tearney GJ, Rowe SM. (2014) A functional anatomic defect of the cystic fibrosis airway, Am J Resp Crit Care Med, 190(4):421-32.
  20. Nance E, Zhang C, Shih T-Y, Xu Q, Schuster BS, Hanes J. (2014) Brain-penetrating nanoparticles improve paclitaxel efficacy in malignant glioma following local administration, ACS Nano, 8(10):10655-64.
  21. Akgul Y, Word A, Ensign LM, Yamaguchi Y, Lydon J, Hanes J, Mahendroo M. (2014) Hyaluronan in cervical epithelia protects against infection mediated preterm birth, J Clin Invest, 124(12):5481-9.
  22. Ensign LM, Lai SK, Wang Y-Y, Yang M, Mert O, Hanes J, Cone R. (2014) Pretreatment of human cervicovaginal mucus with Pluronic F127 enhances nanoparticle penetration without compromising mucus barrier properties to herpes simplex virus, Biomacromolecules, 15(12):4403-9.
  23. Schneider CS, Perez JG, Cheng E, Zhang C, Mastorakos P, Hanes J, Winkles JA, Woodworth GF, Kim AJ. (2014) Minimizing the non-specific binding of nanoparticles to the brain enables active targeting of Fn14-positive glioblastoma cells, Biomaterials, 42:42-51.
  24. Li Y, San BH, Kessler JL, Kim JH, Xu Q, Hanes J, Yu SM. (2014) Non-covalent photo-patterning of gelatin matrices using caged collagen mimetic peptides, Macromol Biosci, 15(1):52-62.
  25. Yu T, Chan KW, Anonuevo A, Song X, Schuster BS, Chattopadhyay S, Xu Q, Oskolkov N, Patel H, Ensign LM, van Zjil PC, McMahon MT, Hanes J. (2014) Liposome-based mucus-penetrating particles (MPP) for mucosal theranostics: demonstration of diamagnetic chemical exchange saturation transfer (diaCEST) magnetic resonance imaging (MRI), Nanomedicine, 11(2):401-5.
  26. Maisel K, Ensign L, Reddy M, Cone R, Hanes J. (2014) Effect of surface chemistry on nanoparticle interaction with gastrointestinal mucus and distribution in the gastrointestinal tract following oral and rectal administration in the mouse, J Control Release, 197:48-57.
  27. Pease ME, Oglesby EN, Cone-Kimball E, Jefferys JL, Steinhart MR, Kim AJ, Hanes J, Quigley HA. (2014) Scleral permeability varies by mouse strain and is decreased by chronic experimental glaucoma, Invest Ophthalmol Vis Sci, 55(4):2564-73.