Publications 2012

  1. Nance EA, Woodworth GF, Sailor KA, Shih T-Y, Xu Q, Swaminathan G, Xiang D, Eberhart C, and Hanes J.(2012) A Dense Poly(Ethylene Glycol) Coating Improves Penetration of Large Polymeric Nanoparticles Within Brain Tissue. Sci. Transl. Med. 4, 149ra119
  2. Ensign LM, Tang BC, Wang Y-Y, Tse TA, Hoen T, Cone R, Hanes J, (2012) Mucus-penetrating particles for vaginal drug delivery protect against HSV-2, Sci Transl Med, 4: 138ra79.
  3. Ensign LM, Cone R, Hanes J, (2012) Oral Drug Delivery with Polymeric Nanoparticles: The Gastrointestinal Mucus Barriers, Adv Drug Del Rev, 64: 557-570.
  4. Kim AJ, Boylan NJ, Suk JS, Lai SK, Hanes J, (2012) Non-degradative Intracellular Trafficking of Highly Compacted Polymeric DNA Nanoparticles, J Controlled Rel, 158: 102-107.
  5. Iezzi R, Guru BR, Glybina IV, Mishra MK, Kennedy A, Kannan RM, (2012) Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration. Biomaterials, 33:979-88.
  6. Mishra MK, Gérard HC, Whittum-Hudson JA, Hudson AP, Kannan RM, (2012) Dendrimer-enabled modulation of gene expression in Chlamydia trachomatis. Mol Pharm, 9:413-21.
  7. Bosnjakovic A, Mishra MK, Han HJ, Romero R, Kannan RM. (2012) A dendrimer-based immunosensor for improved capture and detection of tumor necrosis factor-α cytokine. Anal Chim Acta, 720:118-25.
  8. Kannan S, Dai H, Navath RS, Balakrishnan B, Jyoti A, Janisse J, Romero R, Kannan RM. (2012) Dendrimer-based postnatal therapy for neuroinflammation and cerebral palsy in a rabbit model. Sci Transl Med, 4:130-46.
  9. Matthaei M, Meng H, Bhutto I, Xu Q, Hanes J, Jun AS (2012) Systematic assessment of microneedle injection into the mouse cornea, Eur. J. Med. Res. 17: 19
  10. Boylan NJ, Kim AJ, Suk JS,  Adstamongkonkul P, Simons BW, Lai SK, Cooper MJ, Hanes J (2012) Enhancement of Airway Gene Transfer by DNA Nanoparticles Using A pH-Responsive Block Copolymer of Polyethylene glycol and Poly-L-lysine, Biomaterials, 33: 2361-2371.
  11. Mert O, Lai SK, Ensign L, Yang M, Wang YY, Wood J, Hanes J. (2012) A poly(ethylene glycol)-based surfactant for formulation of drug-loaded mucus penetrating particles.  J Controlled Rel, 157:455-460.
  12. Boylan NJ, Suk JS, Tang BC, Jelinek R, Lai SK, Hanes J. (2012) Highly Compacted DNA Nanoparticles with Low MW PEG Coatings: In vitro, ex vivo and in vivo evaluation, .  J Controlled Rel, 157:72-79.
  13. Suh J, An Y, Tang, B, Dempsy C, Huang F, Hanes J, (2012) Real-time gene delivery vector tracking in the endo-lysosomal pathway of live cells, Microsc Res Tech, 75: 691-697.
  14. Yu T, Wang Y-Y, Yang M, Zhong W, Pulicare S, Choi W-J, Mert O, Fu J, Lai SK, Hanes J, (2012) Biodegradable mucus-penetrating nanoparticles composed of diblock copolymers of polyethylene glycol and poly(lactic-co-glycolic acid), Drug Del Transl Res, 2: 124-128.
  15. Navarrette C, Sisson J, Nance E, Hanes J, Wyatt T (2012) Particulate matter in cigarette smoke increases ciliary axoneme beating through mechanical stimulation, J Aero Med Pulm Drug Del, 25:159-168.
  16. Jachak A, Lai SK, Suk JS, Biswal S, Breysse P, Hanes J. (2012)  Transport of Metal Oxide Nanoparticles and Single-walled Carbon Nanotubes in Human Mucus Nanotoxicology, 6:614-622.
  17. Burke CW, Suk JS, Kim A, Hsiang Y-HJ, Klibanov AL, Hanes J, Price RJ (2012) Markedly Enhanced Skeletal Muscle Transfection Achieved by the Ultrasound-Targeted Delivery of Non-Viral Gene Nanocarriers with Microbubbles, J Controlled Rel, 162:414-421.
  18. Kim AJ, Hanes J (2012) The Emergence of Multiple Particle Tracking in Intracellular Trafficking of Nanomedicines Biophys Rev, 4:83-92.
  19. Ensign LM, Schneider C, Suk JS, Cone R, Hanes J (2012) Mucus penetrating particles: Biophysical tool and method of drug and gene delivery Adv Mater, 24: 3887-3894
  20. Iwase T, Fu J, Yoshida T, Muramatsu D, Miki A, Hashida N, Oveson B, Nadri A, Shen J, Han B, Wu M, Semenza G, Hanes J, Campochiaro PA, Safe and effective polymeric-doxorubicin conjugate nanoparticles for prolonged antiangiogenic activity in the eye, submitted.
  21. Yang M, Wang Y-Y, Lai SK, Yu T, Zeng Q, Miao B, Ensign L, Chih-Yin J, Wu T-C, Hung C-F, Hanes J, Vaginal delivery of paclitaxel via mucus penetrating nanoparticles suppresses cervical tumor growth, submitted.
  22. Mumper RJ, Hook SS, Wang AZ, Bulte JWM, Patri AK, Uckun FM, Cryns VL, Hanes J, Akin D, Gharkholo N, Goldberg MS, A bucket list for biotargeted nanomedicine: Six tenets before you begin, submitted.
  23. Wang Y-Y, Lai SK, Ensign L, Zhong W, Cone R, Hanes J, Mucus microstructure is remarkably pH-independent, submitted.
  24. Yang M, Lai SK, Wang Y-Y, Happe C, Zhong W, Zhang M, Hanes J, Polyvinyl alcohol coating immobilizes nanoparticles in human mucus, submitted.
  25. Chan KWY, Liu G, Song X, Kim H, Yu T, Arifin DR, Gilad AA, Hanes J, Walczak P, van Zijl PCM, JWM Bulte, MT McMahon, In vivo sensing of transplanted cell viability using microcapsules and MRI detectable pH nanosensors, submitted.